AlloBase Database Search

Protein Search

Search the proteins table with filters based on protein properties and family classification

Basic Protein Information

Protein Name

Gene Name

UniProt ID

Protein Family & Classification

Protein Family Any Family Kinase GPCR Ion Channel Nuclear Receptor Protease Phosphatase Transcription Factor Transporter Chaperone

Sequence Length

to

Reset Search Proteins

Drug Search

Search allosteric drugs by name, target, mechanism, or clinical status

Drug Information

Drug Name

DrugBank ID

Target & Mechanism

Target Protein

Mechanism Any Mechanism Allosteric Inhibitor Allosteric Activator Allosteric Modulator

Clinical Status Any Status Approved Clinical Trials Preclinical

Reset Search Drugs

Allosteric Site Search

Search allosteric binding sites by protein, PDB structure, or validation method

Site Information

Target Protein

PDB ID

Confidence Score

to

Experimental Validation

Validation Method Any Method X-ray Crystallography Cryo-EM NMR Spectroscopy HDX-MS

Residue Count

to

Reset Search Sites

Network Search

Search allosteric communication networks by properties and pathway characteristics

Network Identification

Network ID

Protein/Gene

PDB ID

Network Properties

Communication Strength

to

Pathway Length

to

Conservation Score

to

Validation & Methods

Validation Status Any Status High Medium Low

Prediction Method Any Method Dijkstra Shortest Path Fallback Algorithm Enhanced Algorithm

Reset Search Networks

Advanced Multi-Table Search

Search across multiple tables to find complex relationships between proteins, drugs, and sites

Cross-Table Relationships

Protein/Gene

Drug Name

Target & Mechanism Filters

Protein Family Any Family Kinase GPCR Ion Channel Nuclear Receptor

Drug Mechanism Any Mechanism Allosteric Inhibitor Allosteric Activator Allosteric Modulator

Clinical Status Any Status Approved Clinical Trials Preclinical

Reset Advanced Search