AlloBase integrates 1,457 proteins with 878 allosteric sites across 11 protein families from real experimental data.
AlloBase provides real curated data from scientific literature and databases
Covering 11 protein families with 1,457 total proteins.
Top families: Kinase, GPCR, Ion Channel, Scaffold Protein...5,864 validated allosteric drugs with clinical annotations and target information.
Including FDA-approved and clinical trial compounds864 curated allosteric communication pathways with strength scores.
Residue-level signaling pathways975 PDB structures with experimental data.
X-ray, Cryo-EM, and NMR structuresComputational assessment of allosteric site druggability.
Supporting drug discovery effortsRESTful API for programmatic access to all AlloBase data.
JSON format with pagination support Try APIAccess AlloBase data through multiple interfaces and formats
Explore AlloBase through our intuitive web interface with advanced search, filtering, and visualization capabilities.
Access AlloBase data programmatically through our RESTful API. All responses are in JSON format.
GET /index.php?endpoint=proteinsGET /index.php?endpoint=drugs&clinical_status=approvedGET /index.php?endpoint=sites&min_confidence=0.8GET /index.php?endpoint=networks&limit=50
Export AlloBase data in CSV format for offline analysis and integration with other tools.
Comprehensive documentation and resources to help you make the most of AlloBase.